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The Brain-Gut Connection GLP-1 receptors are also located in the area of the brain that controls nausea (the area postrema)

In the longer term, you could combine a GLP-1 with medication preventing muscle loss, or even more fundamentally, design the weight loss medications to be directed fully to adipose tissue while minimizing muscle loss

The blood smear shows no evidence of macrocytic anemia

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As well as these broader systemic effects, it has also been suggested that DPP-4 may be able to modulate -cell function as part of a paracrine system involving GLP-1 produced locally within the pancreatic islets